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RH

Rafael Holdings, Inc. (RFL)·Q2 2025 Earnings Summary

Executive Summary

  • Q2 FY2025 showed minimal revenue and a net loss driven primarily by a $3.05M non-cash goodwill impairment and investment fair value movements; revenue was $0.08M, net loss attributable was $(4.64)M ($0.19 per share) .
  • Liquidity remains solid with $48.3M in cash and cash equivalents at quarter-end (vs. $8.2M in Q1, reflecting reallocation from marketable securities) .
  • Strategic path unchanged: management reiterated expectations for the TransportNPC 48-week interim analysis of Trappsol Cyclo in mid-2025 and intent to focus the company on Cyclo’s lead program post-merger; the merger subsequently closed on March 26, 2025 (post-quarter) .
  • No formal revenue/EPS guidance or call transcript was provided; near-term stock catalysts remain the NPC1 interim data and integration updates post-merger closing .

What Went Well and What Went Wrong

  • What Went Well

    • Maintained clinical and strategic focus: “Upon closing, the Company’s strategic focus will be on its lead clinical asset, Trappsol Cyclo,” and reiterated mid-2025 interim readout timing .
    • Year-over-year G&A discipline at the quarterly level (flat at $2.6M in both Q2 FY2025 and Q2 FY2024), helping contain operating burn from overhead .
    • Liquidity strengthened to $48.3M of cash and equivalents, positioning the company for the mid-2025 clinical catalyst and integration work .
  • What Went Wrong

    • Bottom-line swing vs. prior year: net loss of $(4.6)M vs. net income of $6.0M in Q2 FY2024, primarily due to fair-value items on Cyclo investments and a $3.05M goodwill impairment this quarter .
    • R&D stepped up (to $0.95M from $0.61M YoY) as consolidated entities (Cornerstone, Day Three) increased activity, elevating operating loss leverage on a very small revenue base .
    • Revenue remains de minimis ($0.08M), rendering traditional operating margin analysis not meaningful and magnifying the impact of non-operating items on EPS .

Financial Results

Trend (last two quarters plus prior quarter)

Metric ($USD Millions, except per share)Q4 FY2024 (ended Jul 31, 2024)Q1 FY2025 (ended Oct 31, 2024)Q2 FY2025 (ended Jan 31, 2025)
Revenue$0.17 $0.13 $0.08
Net (Loss) Income attributable to RFL$(4.47) $(9.01) $(4.64)
Diluted EPS ($)$(0.19) $(0.37) $(0.19)
R&D Expense$1.54 $1.33 $0.95
SG&A Expense$2.33 $2.52 $2.59
Cash & Equivalents (period-end)$2.68 $8.16 $48.32

YoY comparison

Metric ($USD Millions, except per share)Q2 FY2024Q2 FY2025
Revenue$0.07 $0.08
Net (Loss) Income attributable to RFL$6.05 $(4.64)
Diluted EPS ($)$0.25 $(0.19)
R&D Expense$0.61 $0.95
SG&A Expense$2.56 $2.59

Non-operating drivers

Item ($USD Millions)Q4 FY2024Q1 FY2025Q2 FY2025
Goodwill Impairment$3.05
Interest Income$0.61 $0.57 $0.49
Unrealized (Loss)/Gain – Cyclo Equity$(3.16) $(4.37) $0.61
Unrealized (Loss)/Gain – Cyclo Convertible Notes$1.19 $(1.59) $0.49

Notes:

  • Revenue is not a meaningful driver; results are dominated by non-operating fair-value items and non-cash charges .
  • Cash rose sharply in Q2 as available-for-sale securities appear to have been reallocated to cash and equivalents on the balance sheet date .

No segment revenue or KPI breakdowns were provided in the 8-K/press release for Q2 FY2025 .

Guidance Changes

Metric/ItemPeriodPrevious GuidanceCurrent GuidanceChange
Trappsol Cyclo – TransportNPC 48-week interim analysis timingCY2025“Results … expected in the middle of 2025” (Q1 FY2025 PR) “Topline data … expected in the middle of 2025” (Q2 FY2025 PR) Maintained
Merger with Cyclo – closingQ1–Q2 CY2025“Anticipate a shareholder vote … in Q1 2025 and closing promptly” (Q1 PR) “Shareholder vote later this month … anticipate closing promptly” (Q2 PR); merger closed Mar 26, 2025 Achieved (post-quarter)
Strategic focus post-mergerOngoingIntends to focus on Trappsol Cyclo (Q1 PR) Reaffirmed intent to focus on Trappsol Cyclo (Q2 PR) Maintained
Revenue/EPS/Opex/Tax guidanceFY2025Not provided Not provided Maintained (no guidance)

Earnings Call Themes & Trends

No Q2 FY2025 earnings call transcript was furnished in the company’s filings/press materials; themes below synthesize disclosures from the last three quarterly press releases.

TopicPrevious Mentions (Q4 FY2024)Previous Mentions (Q1 FY2025)Current Period (Q2 FY2025)Trend
Clinical progress – NPC1 (Trappsol Cyclo)Fully enrolled pivotal Phase 3; interim results mid-2025 Fully enrolled; interim results mid-2025 Interim results mid-2025 reiterated; positive preliminary observations noted at WORLDS symposium Steady progress
Corporate strategy/focusAdvancing clinical-stage assets; proposed Cyclo merger Post-merger focus to be Trappsol Cyclo; evaluating other assets Post-merger focus reaffirmed Consistent
Capital position$65.9M cash, equivalents & marketable securities at FY-end $54.3M cash, equivalents & marketable securities at Q1 $48.3M cash & equivalents at Q2; AFS line nil on balance sheet Sufficient for near-term catalysts
Portfolio/Consolidation impacts (Cornerstone, Day Three)Consolidation raised R&D/G&A in FY2024 Higher R&D/G&A from consolidated entities R&D and G&A reflect consolidated activity; goodwill impairment recognized Integration ongoing
External events/catalystsExpect interim data mid-2025 Expect interim data mid-2025 Interim analysis mid-2025; merger expected then achieved post-quarter Catalyst approaching

Management Commentary

  • “Upon closing, the Company’s strategic focus will be on its lead clinical asset, Trappsol Cyclo.” – Bill Conkling, CEO .
  • “We are encouraged by the preliminary results presented at the 21st Annual WORLDS symposium in early February from the ongoing Phase 3 TransportNPC Open-Label Sub-Study … topline data from the 48-week interim analysis of 104 enrolled patients is expected in the middle of 2025.” – Bill Conkling, CEO .
  • Post-quarter merger close statement: “The merger with Cyclo Therapeutics is a major step forward in our strategy … and we eagerly await the interim analysis in the middle of 2025.” – Bill Conkling .

Q&A Highlights

  • No Q2 FY2025 earnings call transcript was available; analysis is based on the 8-K/press release disclosures .

Estimates Context

  • We attempted to retrieve S&P Global consensus for Q2 FY2025 revenue and EPS; data was unavailable due to API request limits at the time of query, so we cannot provide a vs-consensus comparison for this quarter. If you would like, we can re-run the request to include consensus comparison once access resets.

Key Takeaways for Investors

  • The investment case is now a binary-ish clinical catalyst plus integration: interim NPC1 data in mid-2025 is the dominant stock driver, with the company now focused on Trappsol Cyclo post-merger .
  • Liquidity of $48.3M as of Q2-end provides runway into the interim readout and near-term integration activities .
  • P&L remains highly sensitive to non-cash fair-value items and impairments given a very small revenue base; quarter-to-quarter EPS variability should be expected .
  • Operating discipline on G&A YoY at the quarterly level is encouraging, but consolidated R&D is trending up, consistent with clinical development focus .
  • No formal financial guidance was issued; near-term catalysts are (1) TransportNPC interim data and (2) execution on post-merger focus, both of which can materially shift sentiment. A clean, positive interim readout would be the key re-rating event .

Additional source documents used for prior-quarter context and post-quarter developments:

  • Q1 FY2025 earnings 8-K/press release (Dec 11, 2024) .
  • Q4/FY2024 earnings 8-K/press release (Nov 6–7, 2024) .
  • Merger completion press release (Mar 26, 2025) .